Genomics

Our publications on genomics

Wu, S. Z., Roden, D. L., Al-Eryani, G., Bartonicek, N., Harvey, K., Cazet, A. S., Chan, C. L., Junankar, S., Hui, M. N., Millar, E. A., Beretov, J., Horvath, L., Joshua, A. M., Stricker, P., Wilmott, J. S., Quek, C., Long, G. V., Scolyer, R. A., Yeung, B. Z., Segara, D., … Swarbrick, A. (2021). Cryopreservation of human cancers conserves tumour heterogeneity for single-cell multi-omics analysis. Genome medicine, 13(1), 81. https://doi.org/10.1186/s13073-021-00885-z

Lin, H. M., Mak, B., Yeung, N., Huynh, K., Meikle, T. G., Mellett, N. A., Kwan, E. M., Fettke, H., Tran, B., Davis, I. D., Mahon, K. L., Zhang, A., Stockler, M. R., Briscoe, K., Marx, G., Crumbaker, M., Stricker, P. D., Du, P., Yu, J., Jia, S., … Horvath, L. G. (2021). Overcoming enzalutamide resistance in metastatic prostate cancer by targeting sphingosine kinase. EBioMedicine, 72, 103625. https://doi.org/10.1016/j.ebiom.2021.103625

Hayes, V., Jaratlerdsiri, W., Jiang, J., Gong, T., Patrick, S., Willet, C., Chew T., Lyons R., Haynes A., Pasqualim G., Louw M., Kench J., Campbell R., Chan E., Wedge D., Sadsad R., Brum I., Mutambirwa S., Stricker P., Bomman R. & Horvath, L. (2021). African-specific prostate cancer molecular taxonomy. Research Square 1 Dec 2021. https://doi.org/10.21203/rs.3.rs-1122619/v1

Lin, H. M., Mak, B., Yeung, N., Huynh, K., Meikle, T. G., Mellett, N. A., Kwan, E. M., Fettke, H., Tran, B., Davis, I. D., Mahon, K. L., Zhang, A., Stockler, M. R., Briscoe, K., Marx, G., Crumbaker, M., Stricker, P. D., Du, P., Yu, J., Jia, S., … Horvath, L. G. (2021). Overcoming enzalutamide resistance in metastatic prostate cancer by targeting sphingosine kinase. EBioMedicine, 72, 103625. https://doi.org/10.1016/j.ebiom.2021.103625

Gong, T., Jaratlerdsiri, W., Jiang, J., Willet, C., Chew, T., Patrick, S. M., Lyons, R. J., Haynes, A. M., Pasqualim, G., Brum, I. S., Stricker, P. D., Mutambirwa, S. B. A., Sadsad, R., Papenfuss, A. T., Bornman, R. M. S., Chan, E. K. F., & Hayes, V. M. (2022). Genome-wide interrogation of structural variation reveals novel African-specific prostate cancer oncogenic drivers. Genome medicine, 14(1), 100. https://doi.org/10.1186/s13073-022-01096-w

Craddock, J., Jiang, J., Patrick, S. M., Mutambirwa, S. B. A., Stricker, P. D., Bornman, M. S. R., Jaratlerdsiri, W., & Hayes, V. M. (2023). Alterations in the Epigenetic Machinery Associated with Prostate Cancer Health Disparities. ancers, 15(13), 3462. https://doi.org/10.3390/cancers15133462

Peters, T. J., Meyer, B., Ryan, L., Achinger-Kawecka, J., Song, J., Campbell, E. M., Qu, W., Nair, S., Loi-Luu, P., Stricker, P., Lim, E., Stirzaker, C., Clark, S. J., & Pidsley, R. (2024). Characterisation and reproducibility of the HumanMethylationEPIC v2.0 BeadChip for DNA methylation profiling. BMC genomics, 25(1), 251. https://doi.org/10.1186/s12864-024-10027-5

Hayes, V., Jiang, J., Tapinos, A., Huang, R., Bornman, R., Stricker, P., Mutambirwa, S., Wedge, D., & Jaratlerdsiri, W. (2024). Kataegis associated mutational processes linked to adverse prostate cancer presentation in African men. Research square, rs.3.rs-4597464. https://doi.org/10.21203/rs.3.rs-4597464/v1

Huang, R., Bornman, M. S. R., Stricker, P. D., Simoni Brum, I., Mutambirwa, S. B. A., Jaratlerdsiri, W., & Hayes, V. M. (2024). The impact of telomere length on prostate cancer aggressiveness, genomic instability and health disparities. Scientific reports, 14(1), 7706. https://doi.org/10.1038/s41598-024-57566-1